Whitey and his girlfriend become mob targets after he witnesses a murder during his pickup of stolen merchandise. Whitey and his girlfriend are forced to enter the witness protection program.

O'brien must re-evaluate his relationship with Nicole when she becomes pregnant. In addition, O'brien and Giambone investigate a gruesome assault tied to a crooked restaurant owner who is indebted to a dying loanshark.

O'brien and Giambone search for the criminals who shot Lt. Hogan during a holdup.

A young woman confesses to Father Torres that she witnessed her brother kill a friend over a disagreement during a mugging.

Carson feels responsible when Colby is shot while investigating a robbery.

O'brien and Giambone investigate the deaths of six illegal aliens who died in a shipping container trying to enter the country. Both are convinced another 'shipment' is on the way.

While investigating an unusual death, Kevin and Frank become curious about a wealthy family's effort to keep their dead father's memory alive. Frank is pursued by payroll because of his mounting debt.

A Columbian detective helps the precinct apprehend members of a drug ring when several people are killed by a lone gunman during a cocaine operation.

A priest helps the police find the hit-and-run driver who killed a young woman. Meanwhile, a women visits Lt. Hogan and claims to be his daughter.

Kevin and Frank investigate when a real estate fraud sends a psychopath on a killing spree.

A man attempts to protect his wife after she witnesses the murder of a drug dealer.

The officers of Mid-South reminisce about their past experiences when the precinct is about to be shut down forcing the officers who had worked together for years to be scattered to other precincts.